Mississippi River Cruises Overview

Stretching for 2,350 miles down the United States, from Minnesota's Lake Itasca to the Gulf of Mexico, the "Mighty Mississippi" offers a different type of cross-country journey for the curious explorer—one that allows you to be immersed in American history and culture.

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Featured Sailings

Showing results 1 - 100 of 1109 Sailings for United States view all

Date Ship Title Price
220808

Aug

8


2022

Crystal Serenity®

25-night Grand Journey – Splendors of North America Cruise

Crystal Cruises® | Crystal Serenity® | Vancouver/New York City

from

$8,502

Details

ID: 1358994

220815

Aug

15


2022

Crystal Serenity®

18-night Panama Canal and Central America Cruise

Crystal Cruises® | Crystal Serenity® | Los Angeles/New York City

from

$6,399

Details

ID: 1358995

221021

Oct

21


2022

Crystal Serenity®

14-night Eastern Seaboard Heritage Cruise

Crystal Cruises® | Crystal Serenity® | Quebec City/Miami

from

$4,899

Details

ID: 1359004

220916

Sep

16


2022

Crystal Endeavor®

14-night American East Coast Discovery Cruise

Crystal Cruises® | Crystal Endeavor® | Montreal/West Palm Beach

from

$13,599

Details

ID: 1369388

220220

Feb

20


2022

Anthem of the Seas

7-night Bahamas Cruise

Royal Caribbean International® | Anthem of the Seas | Roundtrip Cape Liberty Cruise Port (NY Harbor)

Call for Price

Details

ID: 1370753

220227

Feb

27


2022

Anthem of the Seas

7-night Bahamas Cruise

Royal Caribbean International® | Anthem of the Seas | Roundtrip Cape Liberty Cruise Port (NY Harbor)

from

$483

Details

ID: 1370754

220306

Mar

6


2022

Anthem of the Seas

7-night Bahamas Cruise

Royal Caribbean International® | Anthem of the Seas | Roundtrip Cape Liberty Cruise Port (NY Harbor)

Call for Price

Details

ID: 1370755

220313

Mar

13


2022

Anthem of the Seas

7-night Bahamas Cruise

Royal Caribbean International® | Anthem of the Seas | Roundtrip Cape Liberty Cruise Port (NY Harbor)

from

$571

Details

ID: 1370757

220327

Mar

27


2022

Anthem of the Seas

7-night Bahamas Cruise

Royal Caribbean International® | Anthem of the Seas | Roundtrip Cape Liberty Cruise Port (NY Harbor)

from

$545

Details

ID: 1370759

220403

Apr

3


2022

Anthem of the Seas

7-night Bahamas Cruise

Royal Caribbean International® | Anthem of the Seas | Roundtrip Cape Liberty Cruise Port (NY Harbor)

Call for Price

Details

ID: 1370760

220410

Apr

10


2022

Anthem of the Seas

7-night Bahamas Cruise

Royal Caribbean International® | Anthem of the Seas | Roundtrip Cape Liberty Cruise Port (NY Harbor)

Call for Price

Details

ID: 1370761

220417

Apr

17


2022

Anthem of the Seas

7-night Bahamas Cruise

Royal Caribbean International® | Anthem of the Seas | Roundtrip Cape Liberty Cruise Port (NY Harbor)

Call for Price

Details

ID: 1370762

220317

Mar

17


2022

Enchantment of the Seas

8-night Southeast Coast and Bahamas Cruise

Royal Caribbean International® | Enchantment of the Seas | Roundtrip Baltimore

from

$509

Details

ID: 1371667

220128

Jan

28


2022

Enchantment of the Seas

8-night Southeast Coast and Perfect Day Cruise

Royal Caribbean International® | Enchantment of the Seas | Roundtrip Baltimore

from

$439

Details

ID: 1371797

220325

Mar

25


2022

Enchantment of the Seas

8-night Southeast Coast and Perfect Day Cruise

Royal Caribbean International® | Enchantment of the Seas | Roundtrip Baltimore

from

$544

Details

ID: 1371798

220414

Apr

14


2022

Enchantment of the Seas

8-night Southeast Coast and Bahamas Cruise

Royal Caribbean International® | Enchantment of the Seas | Roundtrip Baltimore

Call for Price

Details

ID: 1371799

220624

Jun

24


2022

American Jazz

21-night Complete Mississippi River Cruise

American Cruise Lines | American Jazz | New Orleans/St. Paul

Call for Price

Details

ID: 1375726

220507

May

7


2022

Viking Octantis

7-night Niagara and the Great Lakes Cruise

Viking Cruises | Viking Octantis | Milwaukee/Toronto

from

$6,795

Details

ID: 1377074

220430

Apr

30


2022

Viking Octantis

7-night Niagara and the Great Lakes Cruise

Viking Cruises | Viking Octantis | Toronto/Milwaukee

from

$6,495

Details

ID: 1377075

220610

Jun

10


2022

American Pride

7-night Columbia and Snake Rivers Cruise

American Cruise Lines | American Pride | Portland/Clarkston

from

$5,075

Details

ID: 1377858

220418

Apr

18


2022

Viking Octantis

12-night Canadian Discovery Cruise

Viking Cruises | Viking Octantis | New York City/Toronto

Call for Price

Details

ID: 1378554

220810

Aug

10


2022

American Splendor (formerly America®)

14-night Grand Heartland Cruise

American Cruise Lines | American Splendor (formerly America®) | St. Paul/New Orleans

from

$11,255

Details

ID: 1379468

220430

Apr

30


2022

American Star

7-night Historic South and Golden Isles Cruise

American Cruise Lines | American Star | Jacksonville/Fort Sumter, SC

Call for Price

Details

ID: 1379471

220225

Feb

25


2022

Enchantment of the Seas

8-night Southeast Coast and Perfect Day Cruise

Royal Caribbean International® | Enchantment of the Seas | Roundtrip Baltimore

from

$459

Details

ID: 1379994

220514

May

14


2022

Viking Octantis

7-night Niagara and the Great Lakes Cruise

Viking Cruises | Viking Octantis | Toronto/Milwaukee

from

$7,295

Details

ID: 1380037

220611

Jun

11


2022

Viking Octantis

7-night Niagara and the Great Lakes Cruise

Viking Cruises | Viking Octantis | Toronto/Milwaukee

from

$7,295

Details

ID: 1380040

220709

Jul

9


2022

Viking Octantis

7-night Niagara and the Great Lakes Cruise

Viking Cruises | Viking Octantis | Toronto/Milwaukee

from

$9,595

Details

ID: 1380041

220521

May

21


2022

Viking Octantis

7-night Great Lakes Explorer Cruise

Viking Cruises | Viking Octantis | Milwaukee/Thunder Bay

from

$6,995

Details

ID: 1380042

220618

Jun

18


2022

Viking Octantis

7-night Great Lakes Explorer Cruise

Viking Cruises | Viking Octantis | Milwaukee/Thunder Bay

from

$6,995

Details

ID: 1380043

220716

Jul

16


2022

Viking Octantis

7-night Great Lakes Explorer Cruise

Viking Cruises | Viking Octantis | Milwaukee/Thunder Bay

from

$6,995

Details

ID: 1380044

220730

Jul

30


2022

Viking Octantis

7-night Great Lakes Explorer Cruise

Viking Cruises | Viking Octantis | Milwaukee/Thunder Bay

from

$6,695

Details

ID: 1380045

220813

Aug

13


2022

Viking Octantis

7-night Great Lakes Explorer Cruise

Viking Cruises | Viking Octantis | Milwaukee/Thunder Bay

from

$6,695

Details

ID: 1380046

220827

Aug

27


2022

Viking Octantis

7-night Great Lakes Explorer Cruise

Viking Cruises | Viking Octantis | Milwaukee/Thunder Bay

from

$6,695

Details

ID: 1380047

220910

Sep

10


2022

Viking Octantis

7-night Great Lakes Explorer Cruise

Viking Cruises | Viking Octantis | Milwaukee/Thunder Bay

from

$6,995

Details

ID: 1380048

220528

May

28


2022

Viking Octantis

7-night Undiscovered Great Lakes Cruise

Viking Cruises | Viking Octantis | Thunder Bay/Milwaukee

from

$6,995

Details

ID: 1380052

220625

Jun

25


2022

Viking Octantis

7-night Undiscovered Great Lakes Cruise

Viking Cruises | Viking Octantis | Thunder Bay/Milwaukee

from

$6,995

Details

ID: 1380053

220723

Jul

23


2022

Viking Octantis

7-night Undiscovered Great Lakes Cruise

Viking Cruises | Viking Octantis | Thunder Bay/Milwaukee

from

$6,995

Details

ID: 1380054

220806

Aug

6


2022

Viking Octantis

7-night Undiscovered Great Lakes Cruise

Viking Cruises | Viking Octantis | Thunder Bay/Milwaukee

from

$6,695

Details

ID: 1380055

220820

Aug

20


2022

Viking Octantis

7-night Undiscovered Great Lakes Cruise

Viking Cruises | Viking Octantis | Thunder Bay/Milwaukee

from

$6,695

Details

ID: 1380056

220903

Sep

3


2022

Viking Octantis

7-night Undiscovered Great Lakes Cruise

Viking Cruises | Viking Octantis | Thunder Bay/Milwaukee

from

$6,695

Details

ID: 1380057

220917

Sep

17


2022

Viking Octantis

7-night Undiscovered Great Lakes Cruise

Viking Cruises | Viking Octantis | Thunder Bay/Milwaukee

from

$6,995

Details

ID: 1380058

220604

Jun

4


2022

Viking Octantis

7-night Niagara and the Great Lakes Cruise

Viking Cruises | Viking Octantis | Milwaukee/Toronto

from

$7,295

Details

ID: 1380059

220702

Jul

2


2022

Viking Octantis

7-night Niagara and the Great Lakes Cruise

Viking Cruises | Viking Octantis | Milwaukee/Toronto

from

$10,995

Details

ID: 1380061

220924

Sep

24


2022

Viking Octantis

7-night Niagara and the Great Lakes Cruise

Viking Cruises | Viking Octantis | Milwaukee/Toronto

from

$10,995

Details

ID: 1380062

221001

Oct

1


2022

Viking Octantis

12-night Canadian Discovery Cruise

Viking Cruises | Viking Octantis | Toronto/New York City

Call for Price

Details

ID: 1380063

220709

Jul

9


2022

American West (formerly Queen of the West)

7-night Columbia and Snake Rivers Cruise

American Cruise Lines | American West (formerly Queen of the West) | Portland/Clarkston

Call for Price

Details

ID: 1380412

220120

Jan

20


2022

Enchantment of the Seas

8-night Southeast Coast and Bahamas Cruise

Royal Caribbean International® | Enchantment of the Seas | Roundtrip Baltimore

from

$439

Details

ID: 1383737

220217

Feb

17


2022

Enchantment of the Seas

8-night Southeast Coast and Bahamas Cruise

Royal Caribbean International® | Enchantment of the Seas | Roundtrip Baltimore

Call for Price

Details

ID: 1383738

220703

Jul

3


2022

American Constitution

10-night Grand New England Cruise

American Cruise Lines | American Constitution | Roundtrip Boston

from

$6,240

Details

ID: 1383814

220312

Mar

12


2022

American Star

7-night Great Rivers of Florida Cruise

American Cruise Lines | American Star | Roundtrip Jacksonville

from

$3,630

Details

ID: 1383815

220611

Jun

11


2022

American Star

7-night New England Islands Cruise

American Cruise Lines | American Star | Roundtrip Providence

from

$4,490

Details

ID: 1383816

220806

Aug

6


2022

American Heritage (formerly Queen of the Mississippi)

10-night Ohio River Cruise

American Cruise Lines | American Heritage (formerly Queen of the Mississippi) | St. Louis/Pittsburgh

Call for Price

Details

ID: 1383817

221015

Oct

15


2022

Viking Mississippi

14-night America's Great River Cruise

Viking Cruises | Viking Mississippi | St. Paul/New Orleans

from

$10,999

Details

ID: 1384112

220917

Sep

17


2022

Viking Mississippi

14-night America's Great River Cruise

Viking Cruises | Viking Mississippi | St. Paul/New Orleans

Call for Price

Details

ID: 1384548

220827

Aug

27


2022

Viking Mississippi

7-night America's Heartland River Cruise

Viking Cruises | Viking Mississippi | St. Louis/St. Paul

from

$5,299

Details

ID: 1384886

220910

Sep

10


2022

Viking Mississippi

7-night America's Heartland River Cruise

Viking Cruises | Viking Mississippi | St. Louis/St. Paul

Call for Price

Details

ID: 1384887

220903

Sep

3


2022

Viking Mississippi

7-night America's Heartland River Cruise

Viking Cruises | Viking Mississippi | St. Paul/St. Louis

Call for Price

Details

ID: 1384888

221001

Oct

1


2022

Viking Mississippi

14-night America's Great River Cruise

Viking Cruises | Viking Mississippi | New Orleans/St. Paul

from

$10,999

Details

ID: 1384889

221029

Oct

29


2022

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | New Orleans/Memphis

Call for Price

Details

ID: 1384890

221112

Nov

12


2022

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | New Orleans/Memphis

Call for Price

Details

ID: 1384892

230121

Jan

21


2023

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | New Orleans/Memphis

from

$4,199

Details

ID: 1384893

230204

Feb

4


2023

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | New Orleans/Memphis

from

$4,199

Details

ID: 1384894

230218

Feb

18


2023

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | New Orleans/Memphis

from

$4,299

Details

ID: 1384895

230304

Mar

4


2023

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | New Orleans/Memphis

from

$4,499

Details

ID: 1384896

230318

Mar

18


2023

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | New Orleans/Memphis

from

$4,899

Details

ID: 1384897

230401

Apr

1


2023

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | New Orleans/Memphis

from

$4,999

Details

ID: 1384898

230415

Apr

15


2023

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | New Orleans/Memphis

from

$5,299

Details

ID: 1384899

230429

Apr

29


2023

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | New Orleans/Memphis

from

$5,299

Details

ID: 1384900

221105

Nov

5


2022

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | Memphis/New Orleans

Call for Price

Details

ID: 1384901

221119

Nov

19


2022

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | Memphis/New Orleans

Call for Price

Details

ID: 1384902

230128

Jan

28


2023

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | Memphis/New Orleans

from

$4,199

Details

ID: 1384903

230211

Feb

11


2023

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | Memphis/New Orleans

from

$4,199

Details

ID: 1384904

230225

Feb

25


2023

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | Memphis/New Orleans

from

$4,299

Details

ID: 1384905

230311

Mar

11


2023

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | Memphis/New Orleans

from

$4,699

Details

ID: 1384906

230325

Mar

25


2023

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | Memphis/New Orleans

from

$4,899

Details

ID: 1384907

230408

Apr

8


2023

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | Memphis/New Orleans

from

$4,999

Details

ID: 1384908

230422

Apr

22


2023

Viking Mississippi

7-night Heart of the Delta River Cruise

Viking Cruises | Viking Mississippi | Memphis/New Orleans

from

$5,299

Details

ID: 1384909

221126

Nov

26


2022

Viking Mississippi

7-night Southern Celebration River Cruise

Viking Cruises | Viking Mississippi | Roundtrip New Orleans

Call for Price

Details

ID: 1384910

221203

Dec

3


2022

Viking Mississippi

7-night Southern Celebration River Cruise

Viking Cruises | Viking Mississippi | Roundtrip New Orleans

Call for Price

Details

ID: 1384912

221210

Dec

10


2022

Viking Mississippi

7-night Mississippi Holiday Season River Cruise

Viking Cruises | Viking Mississippi | New Orleans/Memphis

Call for Price

Details

ID: 1384913

221217

Dec

17


2022

Viking Mississippi

7-night Mississippi Holiday Season River Cruise

Viking Cruises | Viking Mississippi | Memphis/New Orleans

from

$3,999

Details

ID: 1384914

221224

Dec

24


2022

Viking Mississippi

7-night Mississippi Holiday Season River Cruise

Viking Cruises | Viking Mississippi | New Orleans/Memphis

from

$4,399

Details

ID: 1384915

221231

Dec

31


2022

Viking Mississippi

7-night Mississippi Holiday Season River Cruise

Viking Cruises | Viking Mississippi | Memphis/New Orleans

from

$4,399

Details

ID: 1384916

230107

Jan

7


2023

Viking Mississippi

7-night Southern Celebration River Cruise

Viking Cruises | Viking Mississippi | Roundtrip New Orleans

from

$3,699

Details

ID: 1384917

230114

Jan

14


2023

Viking Mississippi

7-night Southern Celebration River Cruise

Viking Cruises | Viking Mississippi | Roundtrip New Orleans

from

$3,699

Details

ID: 1384918

221105

Nov

5


2022

Norwegian Dawn

15-night Transatlantic from Barcelona to Tampa – Bahamas, Spain, and Bermuda Cruise

Norwegian Cruise Line® | Norwegian Dawn | Barcelona/Tampa

from

$1,298

Details

ID: 1385701

220219

Feb

19


2022

Norwegian Getaway

8-night Bahamas Round-trip New York – Great Stirrup Cay, Orlando, and Nassau Cruise

Norwegian Cruise Line® | Norwegian Getaway | Roundtrip New York City

from

$629

Details

ID: 1386179

220227

Feb

27


2022

Norwegian Getaway

7-night Bahamas Round-trip New York – Great Stirrup Cay, Orlando, and Nassau Cruise

Norwegian Cruise Line® | Norwegian Getaway | Roundtrip New York City

from

$549

Details

ID: 1386180

220306

Mar

6


2022

Norwegian Getaway

7-night Bahamas Round-trip New York – Great Stirrup Cay, Orlando, and Nassau Cruise

Norwegian Cruise Line® | Norwegian Getaway | Roundtrip New York City

from

$549

Details

ID: 1386181

220313

Mar

13


2022

Norwegian Getaway

7-night Bahamas Round-trip New York – Great Stirrup Cay, Orlando, and Nassau Cruise

Norwegian Cruise Line® | Norwegian Getaway | Roundtrip New York City

from

$579

Details

ID: 1386182

220320

Mar

20


2022

Norwegian Getaway

7-night Bahamas Round-trip New York – Great Stirrup Cay, Orlando, and Nassau Cruise

Norwegian Cruise Line® | Norwegian Getaway | Roundtrip New York City

from

$579

Details

ID: 1386183

220327

Mar

27


2022

Norwegian Getaway

7-night Bahamas Round-trip New York – Great Stirrup Cay, Orlando, and Nassau Cruise

Norwegian Cruise Line® | Norwegian Getaway | Roundtrip New York City

from

$579

Details

ID: 1386184

220403

Apr

3


2022

Norwegian Getaway

7-night Bahamas Round-trip New York – Great Stirrup Cay, Orlando, and Nassau Cruise

Norwegian Cruise Line® | Norwegian Getaway | Roundtrip New York City

from

$729

Details

ID: 1386185

220803

Aug

3


2022

American Splendor (formerly America®)

7-night Upper Mississippi River Cruise

American Cruise Lines | American Splendor (formerly America®) | Alton/Red Wing

Call for Price

Details

ID: 1386337

220506

May

6


2022

American Constellation

10-night Grand Puget Sound Cruise

American Cruise Lines | American Constellation | Roundtrip Seattle

from

$7,250

Details

ID: 1386338

220426

Apr

26


2022

American Constitution

10-night American Revolution Cruise

American Cruise Lines | American Constitution | Roundtrip Baltimore

from

$6,430

Details

ID: 1386339

220519

May

19


2022

American Harmony

7-night Columbia and Snake Rivers Cruise

American Cruise Lines | American Harmony | Portland/Clarkston

from

$5,765

Details

ID: 1386340

220430

Apr

30


2022

American Star

14-night East Coast Inland Passage Cruise

American Cruise Lines | American Star | Jacksonville/Baltimore

Call for Price

Details

ID: 1386345

220519

May

19


2022

American Independence

6-night Chesapeake Bay Cruise

American Cruise Lines | American Independence | Roundtrip Baltimore

from

$3,640

Details

ID: 1386348

220416

Apr

16


2022

American Independence

7-night Historic South and Golden Isles Cruise

American Cruise Lines | American Independence | Charleston, SC/Fernandina Beach

from

$5,830

Details

ID: 1386351

Stretching for 2,350 miles down the United States, from Minnesota's Lake Itasca to the Gulf of Mexico, the "Mighty Mississippi" offers a different type of cross-country journey for the curious explorer—one that allows you to be immersed in American history and culture.

All-Travel